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Engineering Creativity for Neuroscience



Small Vessel Myograph


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Small Vessel Myograph measuring system provides recording of contractility of isolated tissue during application of different drugs. Vessel myograph (in other words wire myograph) is a traditional equipment in pharmacological and preclinical research. This technique can be used to investigate different kinds of contractile tissues from various species. Our Small Vessel Myograph system is useful to study vessels, muscles and tissue strips while drugs are applied on them. A simultaneous electrical stimulation can also be carried out on the examined tissue.


            Click on the picture to get it in full size


Small Vessel Myograph recording system consists of the following equipments:


    - Mechanical assembly, containing the heated organ bath.


    - Small Vessel Myograph SVM-1b measuring equipment. This unit provides calibrated analog voltage output to record the

        contractions of the examined tissue on any kind of PC-based data acquisition system. Furthermore there is a built-in

        high resolution and fast analog to digital converter, which is accessible directly via standard USB 2.0 port of a computer.


    - Force Sensor Headstage VMY-1c.


    - Physiological - Biological Temperature Controller TMP-5b. This equipment regulates the temperature of the organ bath.

        This is the universal biological temperature controller of Supertech Instruments, which is involved in the Small Vessel

        Myograph measuring system, as well. On the Temperature Management in Physiology and in Biology page you

        can read the very detailed description of the TMP-5b temperature controller.


    - Recording program: Windows-based data recording and analysis program. It is downloadable as a freeware.


Technical Data


Full scale force of the vessel sensor: 1000 mN


Chamber material: unique stainless steel alloy, fully compatible with the living tissues


Chamber volume: 3.5 ml


Mounting method: pins


Vessel internal diameter: > 600 μm


Vessel adjustment (normalization): manually by a micrometer


Micrometer resolution: 0.01 mm


Temperature range: ambient to 60 Centigrade


Temperature adjustment: in 1 Centigrade steps


Resolution of temperature measurement: 0.1 Centigrade


Hysteresis: max. 0.5 Centigrade


Signal output choice:


    - Analog voltage output: for high resolution and fast measurements


    - Built-in analog to digital converter: for rough and/or pilot measurements


    - DVM on the front plate (3 reading / sec): for normalization of the vessel


Specification of the analog voltage output:


    - Full-scale range of the electronic circuit for the vessel sensor: 2000 mN


    - Analogue output range: +/- 5 V


    - Resolution: 0.02 mN


    - Worst-case error of the full scale value: < 2 %


    - Linearity error maximum: < 2 %


    - Scale factor choice:

        10 V / N

        1 V / N

        0.1 V / N


    - Bandwidth of the analog circuitry: 10 Hz to 500 Hz (factory selectable)


    - Analog output impedance: 300 Ohm


Specification of the built-in analog to digital converter:


    - Data communication: USB 2.0


    - Maximum sampling rate with USB streaming: 100 kHz


    - Resolution 8 bits


Every part of the mechanical assembly is made of stainless steel. The basement of the organ bath is a strong fixing plate standing on three feet. In the middle of the basement there is a heated tissue chamber. The material of the heated chamber is a very special kind of steel alloy, which is fully compatible with the living tissues. The temperature of the heated chamber (organ bath) is regulated with the accuracy of better than 0.5 Centigrade.


Small pieces of vessels can be fixed as rings on two tungsten wires. The internal diameter range of the measurable vessels is 1 to 10 mm. One of the fixing wires is attached to the force sensor. The force sensor is part of the Force Sensor Headstage VMY-1c. The other, opposite holding wire is fixed on the removable upper part on easily adjustable way. The Force Sensor Headstage VMY-1c is fine positioned by a micrometer, providing accurate control of vessel circumference.


The whole upper part of the organ bath, including the force sensor, the Force Sensor Headstage VMY-1c and the opposite holding wire can be removed from the basement in one piece completely. This feature provides a comfortable and precise way to fix the examined tissue on the wires. Removable design of the upper part helps positioning of the preparation on the fixing wires, because the upper part of the organ bath can be put completely on the stage of an operation microscope.


        Click on the picture to get it in full size


There are flexibly adjustable tubes to transport carbogene gas and saline solution into the tissue (organ) bath to maintain the optimal physiological conditions for the tissue. The solution and gas tubes are easily detachable and repositionable on the basement.





You can find the general warranty and shipping conditions in the beginning of the Price List page.


This product has been introduced just now. That is, why the price of the system (except the Physiological - Biological Temperature Controller TMP-5b) is not finalized yet. For the current price information, please contact us.




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